Description

[(6-Chloro[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)-Methyl]Amine Hydrochloride is a high-purity, heterocyclic organic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique fused triazolopyridazine structure makes it a valuable intermediate for synthesizing novel active pharmaceutical ingredients (APIs) with targeted biological activity. This compound is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and life science industries to create new therapeutic candidates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Serves as a building block for creating new pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial manufacturing of complex molecules.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug discovery pipelines.

Basic Information

Product Name	[(6-Chloro[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)-Methyl]Amine Hydrochloride
CAS No.	518050-85-6
Molecular Formula	C7H7Cl2N5
Molecular Weight	232.07 g/mol
Synonyms	1-[(6-Chloro[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methyl]amine hydrochloride; 3-(Aminomethyl)-6-chloro[1,2,4]triazolo[4,3-b]pyridazine hydrochloride; (6-Chloro-s-triazolo[4,3-b]pyridazin-3-yl)methylamine hydrochloride; 6-Chloro-3-(aminomethyl)-[1,2,4]triazolo[4,3-b]pyridazine HCl; 518050-85-6; 6-Chloro-3-(aminomethyl)-1,2,4-triazolo[4,3-b]pyridazine hydrochloride
EINECS	Contact for details

Quality Control

Our [(6-Chloro[1,2,4]Triazolo[4,3-B]Pyridazin-3-Yl)-Methyl]Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.