Description

2-Fluoro-4-Iodo-6-Nitroaniline is a halogenated and nitrated aniline derivative, a versatile and high-value building block in advanced organic synthesis. Its unique structure, featuring fluorine, iodine, and nitro substituents, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for drug discovery programs targeting various disease pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, where its halogenated structure can contribute to biological activity and environmental stability.
• Material Science Research: Acts as a monomer or functionalization agent in the development of specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing groups.
• Dye and Pigment Intermediate: Employed in the synthesis of complex azo dyes and high-performance pigments where the iodine and nitro groups influence color fastness and spectral properties.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling the construction of biaryl and other complex architectures.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D chemists exploring new synthetic methodologies and creating libraries of novel chemical entities for screening.

Basic Information

Product Name	2-Fluoro-4-Iodo-6-Nitroaniline
CAS No.	517920-73-9
Molecular Formula	C6H4FIN2O2
Molecular Weight	282.01 g/mol
Synonyms	2-Fluoro-4-iodo-6-nitrobenzenamine; 4-Amino-3-fluoro-5-iodonitrobenzene; 6-Nitro-2-fluoro-4-iodoaniline; Benzenamine, 2-fluoro-4-iodo-6-nitro-; 3-Fluoro-5-iodo-2-nitroaniline
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Iodo-6-Nitroaniline is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA), including results from HPLC, NMR, and elemental analysis, is supplied with each shipment to guarantee consistent quality, identity, and purity for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.