Description

5-Bromo-n-(tert-Butyl)-2-Methylbenzenesulfonamide is a specialized organic sulfonamide derivative, serving as a critical synthetic intermediate in advanced chemical synthesis. Its value lies in providing a sterically hindered sulfonamide group and a reactive bromine substituent, enabling precise molecular construction. This compound is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting enzyme inhibition.
• Agrochemical Research: Used in developing advanced herbicides, fungicides, and pesticides, leveraging its unique sulfonamide pharmacophore.
• Chemical Synthesis Reagent: Acts as a versatile precursor for coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and for introducing the tert-butylsulfonamide (Bus) protecting group.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced organic materials.
• Academic & R&D: Essential compound for methodological studies in organic synthesis and for exploring new reaction pathways in university and industrial laboratories.

Basic Information

Product Name	5-Bromo-n-(tert-Butyl)-2-Methylbenzenesulfonamide
CAS No.	511529-00-3
Molecular Formula	C11H16BrNO2S
Molecular Weight	306.22 g/mol
Synonyms	5-Bromo-N-tert-butyl-2-methylbenzenesulfonamide; 2-Methyl-5-bromo-N-(1,1-dimethylethyl)benzenesulfonamide; 5-Bromo-2-methyl-N-(tert-butyl)benzenesulfonamide; Benzenesulfonamide, 5-bromo-N-(1,1-dimethylethyl)-2-methyl-; 5-Bromo-N-(tert-butyl)-2-methylbenzene-1-sulfonamide; 5-Bromo-2-methylbenzenesulfonamide, N-tert-butyl derivative; Bus-protected bromobenzene derivative
EINECS	Contact for details

Quality Control

Our 5-Bromo-n-(tert-Butyl)-2-Methylbenzenesulfonamide is produced under strict quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.