Description

Diethyl-(4-([(Tetrahydro-Furan-2-Ylmethyl)-Amino]-Methyl)-Phenyl)-Amine is a specialized tertiary amine derivative featuring a tetrahydrofuran (THF) moiety, serving as a crucial pharmaceutical intermediate and organic synthesis building block. This compound is valued for its unique molecular architecture, which combines a lipophilic diethylamino group with a heterocyclic ether, making it a versatile synthon for constructing complex bioactive molecules. It is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing new active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Ligand Synthesis: Used to prepare complex ligands for catalysis and metal-organic frameworks (MOFs) due to its chelating nitrogen and oxygen donor atoms.
• Agrochemical Research: Serves as a precursor for developing new crop protection agents and plant growth regulators.
• Polymer Modification: Acts as a functional monomer or curing agent to introduce amine functionality into polymer backbones, enhancing material properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and fluorescent tags for biological imaging and diagnostic applications.
• Organic Electronics: Investigated as a component in the synthesis of charge-transport materials for organic light-emitting diodes (OLEDs) and semiconductors.

Basic Information

Product Name	Diethyl-(4-([(Tetrahydro-Furan-2-Ylmethyl)-Amino]-Methyl)-Phenyl)-Amine
CAS No.	510723-76-9
Molecular Formula	C17H28N2O
Molecular Weight	276.42 g/mol
Synonyms	N-[4-(Diethylamino)benzyl]-1-(tetrahydrofuran-2-yl)methanamine; 1-(Tetrahydrofuran-2-yl)-N-[[4-(diethylamino)phenyl]methyl]methanamine; 4-[(Diethylamino)methyl]-N-[(tetrahydrofuran-2-yl)methyl]aniline; N-((4-(Diethylamino)phenyl)methyl)-1-(tetrahydrofuran-2-yl)methanamine; Diethyl-[4-[[(oxolan-2-ylmethyl)amino]methyl]phenyl]amine; (4-{[(Tetrahydrofuran-2-ylmethyl)amino]methyl}phenyl)diethylamine
EINECS	Contact for details

Quality Control

Our Diethyl-(4-([(Tetrahydro-Furan-2-Ylmethyl)-Amino]-Methyl)-Phenyl)-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable performance in your most sensitive synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.