Description

Cyclopentanol, 2-Ethyl-4-[3-(Trimethylsilyl)Propyl]-, (1R,2R,4S)-Rel- (9Ci) is a chiral, organosilicon-substituted cyclopentanol derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block, offering a unique stereodefined framework and a reactive hydroxyl group protected by a trimethylsilylpropyl chain, which can be selectively manipulated. It is primarily needed by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors for the construction of complex, biologically active molecules, chiral ligands, and specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where its specific stereochemistry can influence biological activity and environmental fate.
• Chiral Ligand & Catalyst Precursor: The defined stereocenters make it a valuable starting material for synthesizing novel chiral ligands used in asymmetric catalysis (e.g., hydrogenation, oxidation).
• Specialty Polymer Monomer: Potential use in the development of specialty silicones or hybrid organic-inorganic polymers with tailored properties for high-performance materials.
• Flavor & Fragrance Chemistry: Acts as a precursor for complex, stereospecific odorants and flavor compounds in high-value fragrance creation.
• Academic & Industrial Research: A valuable tool for methodological studies in organic synthesis, including studies on stereoselective reactions and silicon chemistry.

Basic Information

Item	Detail
Product Name	Cyclopentanol, 2-Ethyl-4-[3-(Trimethylsilyl)Propyl]-, (1R,2R,4S)-Rel- (9Ci)
CAS No.	507235-54-3
Molecular Formula	C13H28OSi
Molecular Weight	228.45 g/mol
Synonyms	(1R,2R,4S)-rel-2-Ethyl-4-(3-(trimethylsilyl)propyl)cyclopentanol; rel-(1R,2R,4S)-2-Ethyl-4-[3-(trimethylsilyl)propyl]cyclopentanol; 2-Ethyl-4-(3-trimethylsilylpropyl)cyclopentanol (stereoisomer); Chiral TMS-cyclopentanol derivative; Organosilicon cyclopentanol
EINECS	Contact for details

Quality Control

Our production of Cyclopentanol, 2-Ethyl-4-[3-(Trimethylsilyl)Propyl]-, (1R,2R,4S)-Rel- (9Ci) adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis (HPLC/GC), identity confirmation (NMR, IR), and determination of chemical purity and residual solvents to ensure it meets the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% de (diastereomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.