Description

3-Chloro-4-Fluoro-Benzamidine is a high-purity chemical intermediate characterized by its amidine functional group flanked by halogen substituents. This compound matters for its role as a critical building block in the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate its unique halogenated benzamidine scaffold into target compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the development of protease inhibitors, kinase inhibitors, and other small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and pesticides, leveraging the bioactivity of the halogenated aromatic system.
• Chemical Biology Probe Development: Serves as a precursor for creating labeled compounds or activity-based probes to study enzyme function and mechanism.
• Material Science: Potential building block for advanced polymers or ligands in catalytic systems due to its chelating amidine group.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical reactions.

Basic Information

Product Name	3-Chloro-4-Fluoro-Benzamidine
CAS No.	504404-34-6
Molecular Formula	C7H6ClFN2
Molecular Weight	172.59 g/mol
Synonyms	3-Chloro-4-fluorobenzamidine; 4-Fluoro-3-chlorobenzamidine; Benzenecarboximidamide, 3-chloro-4-fluoro-; (3-Chloro-4-fluorophenyl)methanimidamide; 3-Chloro-4-fluoro-benzenecarboximidamide
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Fluoro-Benzamidine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all test results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.