Description

1-(Bromomethyl)-4-Methyl-2-Nitrobenzene is a versatile brominated aromatic building block of significant importance in advanced organic synthesis. This compound is valued for its reactivity, particularly in nucleophilic substitution and cross-coupling reactions, enabling the construction of complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those containing substituted benzyl or diarylmethane motifs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides, where the bromomethyl group serves as a versatile handle for further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized phosphine ligands or organocatalysts for asymmetric synthesis and metal-catalyzed transformations.
• Material Science Research: Acts as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, or organic electronic materials.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or affinity probes for studying biological targets and pathways.
• Cross-Coupling Reactions: Serves as an electrophilic partner in Suzuki, Stille, or other palladium-catalyzed cross-coupling reactions to form biaryl structures.

Basic Information

Product Name	1-(Bromomethyl)-4-Methyl-2-Nitrobenzene
CAS No.	503856-32-4
Molecular Formula	C8H8BrNO2
Molecular Weight	230.06 g/mol
Synonyms	2-Nitro-4-methylbenzyl bromide; 4-Methyl-2-nitrobenzyl bromide; (4-Methyl-2-nitrophenyl)methyl bromide; α-Bromo-4-methyl-2-nitrotoluene; 2-Nitro-p-methylbenzyl bromide; 1-Bromomethyl-4-methyl-2-nitrobenzene; 4-Methyl-2-nitrobenzylbromide
EINECS	Contact for details

Quality Control

Our 1-(Bromomethyl)-4-Methyl-2-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.