Description

5H-Furo[3,4-B]Pyran-5-One, 2,3,7,7A-Tetrahydro-3-Hydroxy-7-Methyl-2-(1E)-1-Propenyl-, (2R,3R,7R,7Ar)-Rel- (9Ci) is a high-purity, stereochemically defined chiral compound of significant interest in advanced organic synthesis. This molecule serves as a critical building block for the development of complex pharmacologically active agents and fine chemicals. It is primarily sought by pharmaceutical R&D teams and specialty chemical manufacturers engaged in creating novel therapeutic candidates and high-value intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in stereoselective catalytic reactions to construct molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore novel bioactive compound libraries.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic & Industrial R&D: Used in chemical biology and methodological development research within university and corporate laboratories.

Basic Information

Product Name	5H-Furo[3,4-B]Pyran-5-One, 2,3,7,7A-Tetrahydro-3-Hydroxy-7-Methyl-2-(1E)-1-Propenyl-, (2R,3R,7R,7Ar)-Rel- (9Ci)
CAS No.	503178-80-1
Molecular Formula	C11H14O4
Molecular Weight	210.23 g/mol
Synonyms	rel-(2R,3R,7R,7aR)-2,3,7,7a-Tetrahydro-3-hydroxy-7-methyl-2-[(1E)-1-propen-1-yl]furo[3,4-b]pyran-5-one; (2R,3R,7R,7aR)-rel-2,3,7,7a-Tetrahydro-3-hydroxy-7-methyl-2-[(1E)-prop-1-en-1-yl]-5H-furo[3,4-b]pyran-5-one; Furopyranone derivative; Chiral furopyranone intermediate; CAS 503178-80-1
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and analyzed under strict quality management protocols to ensure identity, purity, and stereochemical integrity. Our standard pharmaceutical-grade specifications are designed to meet the rigorous demands of research and pre-clinical development. A comprehensive Certificate of Analysis (COA) detailing identity (IR, NMR), chiral purity (HPLC), and chemical assay is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.