Description

1,3(2H)-Pyridazinedicarboxylic Acid, Tetrahydro-, 1-(1,1-Dimethylethyl) 3-Methyl Ester, (3S)- is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex, biologically active molecules, particularly within the pharmaceutical sector. It is primarily sought after by research institutions and chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of proprietary drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development and discovery of new, high-efficacy crop protection agents and pesticides.
• Asymmetric Synthesis: Serves as a versatile starting material or intermediate for constructing complex molecular architectures with defined stereochemistry.
• Fine Chemical Production: Employed in the manufacture of specialty and custom fine chemicals for research and industrial applications.
• Ligand and Catalyst Development: Potential use in the design and synthesis of novel chiral ligands and organocatalysts.

Basic Information

Product Name	1,3(2H)-Pyridazinedicarboxylic Acid, Tetrahydro-, 1-(1,1-Dimethylethyl) 3-Methyl Ester, (3S)-
CAS No.	503177-95-5
Molecular Formula	C12H20N2O4
Molecular Weight	256.30 g/mol
Synonyms	(3S)-1-(tert-Butyl) 3-Methyl Tetrahydro-1H,3H-pyridazino[1,2-a]pyridazine-1,3-dicarboxylate; (3S)-1-tert-Butyl 3-Methyl 1,2,3,6-Tetrahydropyridazine-1,3-dicarboxylate; tert-Butyl (3S)-3-(methoxycarbonyl)-1,2,3,6-tetrahydropyridazine-1-carboxylate; (S)-1-Boc-3-methyl 1,2,3,6-tetrahydropyridazine-1,3-dicarboxylate; (S)-1-(tert-Butoxycarbonyl)-3-(methoxycarbonyl)-1,2,3,6-tetrahydropyridazine; 503177-95-5; (3S)-1,3(2H)-Pyridazinedicarboxylic acid, tetrahydro-, 1-(1,1-dimethylethyl) 3-methyl ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through advanced analytical techniques including HPLC, chiral HPLC, GC, and NMR to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.