Description

4-(3,5-Dichlorophenoxy)Benzene-1-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative used as a critical building block in advanced organic synthesis. Its value lies in its dual functionality, enabling the introduction of both a sulfonamide linkage and a substituted phenoxy group into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals. The CAS number for this compound is 501697-53-6.

Application

This versatile chemical intermediate is primarily employed in research and development, as well as in the production of high-value specialty chemicals.

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drug candidates, including potential enzyme inhibitors and receptor antagonists.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with specific modes of action.
• Material Science Research: Used in the development of specialty polymers, dyes, and functional materials requiring specific aromatic sulfonyl groups.
• Chemical Biology & Proteomics: Acts as a reactive handle for bioconjugation and the development of chemical probes targeting biological thiols or amines.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CMOs for the production of bespoke molecules for client projects.

Basic Information

Product Name	4-(3,5-Dichlorophenoxy)Benzene-1-Sulfonyl Chloride
CAS No.	501697-53-6
Molecular Formula	C12H7Cl3O3S
Molecular Weight	337.61 g/mol
Synonyms	1-(3,5-Dichlorophenoxy)-4-(chlorosulfonyl)benzene; 4-(3,5-Dichlorophenoxy)benzenesulfonyl chloride; p-(3,5-Dichlorophenoxy)benzenesulfonyl chloride; Benzene-1-sulfonyl chloride, 4-(3,5-dichlorophenoxy)-; 3,5-Dichlorophenyl 4-(chlorosulfonyl)phenyl ether
EINECS	Contact for details

Quality Control

Our production of 4-(3,5-Dichlorophenoxy)Benzene-1-Sulfonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the exacting standards required for pharmaceutical and agrochemical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and strong acid/organic solvent nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.