Description

n-{[(4-Methylphenyl)Amino]Carbonothioyl}-2-Nitrobenzamide is a specialized thiourea derivative characterized by its nitrobenzamide core structure. This compound is of significant interest in advanced chemical synthesis, serving as a key intermediate or precursor for the development of novel active molecules. It is primarily required by research institutions and industrial R&D departments engaged in pharmaceutical discovery, agrochemical development, and materials science. The precise functional groups present in its structure make it a valuable building block for creating compounds with targeted biological or chemical properties.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme inhibition.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators, leveraging its thiourea moiety.
• Chemical Synthesis Building Block: Acts as a versatile reagent for constructing complex heterocyclic compounds in organic chemistry laboratories.
• Material Science Precursor: Potential use in the development of specialty polymers or organic electronic materials due to its aromatic and nitro functional groups.
• Biochemical Probe Development: Utilized in research to create molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	n-{[(4-Methylphenyl)Amino]Carbonothioyl}-2-Nitrobenzamide
CAS No.	501105-47-1
Molecular Formula	C15H13N3O3S
Molecular Weight	315.35 g/mol
Synonyms	N-(4-Methylphenylcarbamothioyl)-2-nitrobenzamide; 1-(4-Methylphenyl)-3-(2-nitrobenzoyl)thiourea; 2-Nitro-N-[(4-methylphenyl)carbamothioyl]benzamide; Thiourea, N-(4-methylphenyl)-N'-(2-nitrobenzoyl)-; 501105-47-1; p-Tolyl 3-(2-nitrobenzoyl)thiourea
EINECS	Contact for details

Quality Control

Our production of n-{[(4-Methylphenyl)Amino]Carbonothioyl}-2-Nitrobenzamide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry to confirm identity and quantify purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We operate under a quality management system aligned with cGMP principles for active pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.