Description

n-{[(3-Acetylphenyl)Amino]Carbonothioyl}-2-Nitrobenzamide is a specialized organic intermediate featuring a nitrobenzamide core functionalized with a thiourea linkage to an acetylphenyl group. This compound matters for its role as a key building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research and development. It is primarily needed by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting specific enzyme pathways.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, or insecticides, leveraging its nitro and thiourea functional groups.
• Chemical Biology Probe: Acts as a scaffold or building block for creating molecular probes to study biological processes and protein interactions.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized azo dyes or pigments due to its aromatic nitro and amide structure.
• Material Science Research: Can be utilized in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), or other advanced functional materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular architecture.

Basic Information

Product Name	n-{[(3-Acetylphenyl)Amino]Carbonothioyl}-2-Nitrobenzamide
CAS No.	501105-19-7
Molecular Formula	C16H13N3O4S
Molecular Weight	343.36 g/mol
Synonyms	N-[(3-Acetylphenyl)carbamothioyl]-2-nitrobenzamide; 2-Nitro-N-[(3-acetylphenyl)carbamothioyl]benzamide; 1-(3-{[(2-Nitrobenzoyl)amino]carbonothioyl}amino)phenyl)ethanone; Thiourea, N-(3-acetylphenyl)-N'-(2-nitrobenzoyl)-; (3-Acetylphenyl)thiourea, N-(2-nitrobenzoyl)- derivative
EINECS	Contact for details

Quality Control

Our n-{[(3-Acetylphenyl)Amino]Carbonothioyl}-2-Nitrobenzamide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our quality systems are designed to support cGMP compliance for pharmaceutical applications and meet the stringent requirements of research and industrial customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.