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7-[(2-Chloro-6-Fluorophenyl)Methoxy]-4-(4-Methoxyphenyl)-8-Methylchromen-2-One CAS NO 500204-71-7


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CAS No.:500204-71-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

7-[(2-Chloro-6-Fluorophenyl)Methoxy]-4-(4-Methoxyphenyl)-8-Methylchromen-2-One is a high-purity, synthetic chromenone derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a critical chemical intermediate or pharmacological reference standard for the synthesis and study of novel therapeutic agents. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical suppliers focused on developing new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

  • Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential active pharmaceutical ingredients (APIs).
  • Medicinal Chemistry Research: Used as a core scaffold or precursor for structure-activity relationship (SAR) studies to optimize biological activity.
  • Reference Standard: Employed as an analytical standard in HPLC, LC-MS, or NMR for method development, validation, and quality control of related compounds.
  • Biochemical Tool Compound: Investigated for modulating specific biological pathways or enzyme targets in preclinical research.
  • Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.

Basic Information

Product Name 7-[(2-Chloro-6-Fluorophenyl)Methoxy]-4-(4-Methoxyphenyl)-8-Methylchromen-2-One
CAS No. 500204-71-7
Molecular Formula C24H18ClFO4
Molecular Weight 424.85 g/mol
Synonyms 7-[(2-Chloro-6-fluorophenyl)methoxy]-4-(4-methoxyphenyl)-8-methyl-2H-chromen-2-one; 7-[(2-Chloro-6-fluorobenzyl)oxy]-4-(4-methoxyphenyl)-8-methylchromen-2-one; 4-(4-Methoxyphenyl)-7-[(2-chloro-6-fluorophenyl)methoxy]-8-methyl-2H-1-benzopyran-2-one; 8-Methyl-7-[(2-chloro-6-fluorobenzyl)oxy]-4-(4-methoxyphenyl)coumarin; Chromen-2-one, 7-[(2-chloro-6-fluorophenyl)methoxy]-4-(4-methoxyphenyl)-8-methyl-; CAS 500204-71-7
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Quality Control

Our 7-[(2-Chloro-6-Fluorophenyl)Methoxy]-4-(4-Methoxyphenyl)-8-Methylchromen-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Retention time corresponds to reference standard
Identification (IR) Spectrum matches reference
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Single Unknown Impurity ≤ 0.5%
Residual Solvents (GC) Complies with ICH Q3C guidelines
Loss on Drying ≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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