Description

Methyl (6-Chloro-7-Hydroxy-4-Methyl-2-Oxo-2H-Chromen-3-Yl)Acetate is a high-purity chromene derivative, a crucial synthetic intermediate in advanced organic chemistry. Its value lies in its functionalized coumarin scaffold, which serves as a versatile building block for the development of novel active compounds. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to create new molecules with targeted biological or material properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways where the coumarin core is pharmacologically active.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, or plant growth regulators that leverage its heterocyclic structure.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct more elaborate molecular architectures due to its reactive ester and hydroxyl functional groups.
• Material Science Precursor: Serves as a starting material for synthesizing organic dyes, fluorescent markers, or photostable polymers.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting fundamental research in medicinal and synthetic chemistry.

Basic Information

Item	Details
Product Name	Methyl (6-Chloro-7-Hydroxy-4-Methyl-2-Oxo-2H-Chromen-3-Yl)Acetate
CAS No.	500203-85-0
Molecular Formula	C₁₃H₁₁ClO₅
Molecular Weight	282.68 g/mol
Synonyms	Methyl 2-(6-Chloro-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl)acetate; 3-(Carboxymethyl)-6-chloro-7-hydroxy-4-methylcoumarin methyl ester; 6-Chloro-7-hydroxy-4-methyl-2-oxo-2H-chromene-3-acetic acid methyl ester; Methyl 6-chloro-7-hydroxy-4-methyl-2-oxo-2H-chromene-3-acetate; 3-Acetic acid, 6-chloro-7-hydroxy-4-methyl-2-oxo-2H-chromen-3-yl, methyl ester; Chromene-3-acetic acid derivative
EINECS	Contact for details

Quality Control

Our Methyl (6-Chloro-7-Hydroxy-4-Methyl-2-Oxo-2H-Chromen-3-Yl)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.