Description

19,20,22,23-Tetrahydro-12H-7,11-Nitrilo-6H-Dibenzo[B,K][1,4,7,10,13]Pentaoxacycloicosin is a sophisticated macrocyclic polyether compound, also known as a cryptand or crown ether derivative, valued for its exceptional ability to selectively bind specific cations. This property makes it a critical complexing agent and phase-transfer catalyst in advanced chemical synthesis and separation processes. It is essential for researchers and manufacturers in the pharmaceutical, fine chemical, and materials science sectors who require precise molecular recognition and controlled reactivity.

Application

• Phase-Transfer Catalysis (PTC): Facilitates reactions between reagents in immiscible phases, enhancing yields and selectivity in organic synthesis.
• Ion-Selective Complexation: Acts as a host molecule in the development of sensors, electrodes, and extraction systems for specific metal ions.
• Pharmaceutical Intermediate Synthesis: Used in the precise construction of complex drug molecules, particularly where alkali or alkaline earth metal templating is required.
• Polymer & Materials Science: Serves as a building block or modifier for creating functional polymers, membranes, and advanced materials with tailored properties.
• Analytical Chemistry: Employed as a component in chromatographic stationary phases or as a masking agent in spectroscopic analysis.
• Catalysis Research: Provides a well-defined coordination environment for developing novel homogeneous catalysts.

Basic Information

Product Name	19,20,22,23-Tetrahydro-12H-7,11-Nitrilo-6H-Dibenzo[B,K][1,4,7,10,13]Pentaoxacycloicosin
CAS No.	59945-37-8
Molecular Formula	C22H27NO5
Molecular Weight	385.46 g/mol
Synonyms	Cryptand 222; Kryptofix 222; 4,7,13,16,21,24-Hexaoxa-1,10-diazabicyclo[8.8.8]hexacosane; 1,10-Diaza-4,7,13,16,21,24-hexaoxabicyclo[8.8.8]hexacosane; K 222; N,N'-Bis(2-(2-(2-hydroxyethoxy)ethoxy)ethyl)-4,13-diaza-18-crown-6; Diaz-18-crown-6 derivative; Bicyclic polyether diamine
EINECS	Contact for details

Quality Control

Our production of 19,20,22,23-Tetrahydro-12H-7,11-Nitrilo-6H-Dibenzo[B,K][1,4,7,10,13]Pentaoxacycloicosin adheres to a stringent quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and elemental analysis. We provide detailed Certificates of Analysis (COA) to ensure traceability and compliance with your research or cGMP-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.