Description

6,7-Dihydroxy-4H-1-Benzopyran-4-One is a high-purity flavonoid derivative, also known as esculetin, valued for its role as a key synthetic intermediate and bioactive compound. Its significance lies in its versatile chemical functionality, which enables the development of advanced materials and active pharmaceutical ingredients (APIs). This product is essential for research and manufacturing in the pharmaceutical, nutraceutical, and fine chemical industries, where precise chemical structure and purity are critical.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of coumarin-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and inhibitor in studies related to enzyme activity, oxidative stress, and inflammation pathways.
• Cosmetic & Personal Care: Incorporated into formulations for its antioxidant properties and potential skin-brightening effects.
• Nutraceutical Development: Serves as a precursor or active component in dietary supplements targeting vascular health and antioxidant support.
• Fine Chemical Synthesis: Employed in organic synthesis to create complex molecules for agrochemicals and specialty materials.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories.

Basic Information

Product Name	6,7-Dihydroxy-4H-1-Benzopyran-4-One
CAS No.	59887-94-4
Molecular Formula	C9H6O4
Molecular Weight	178.14 g/mol
Synonyms	Esculetin; 6,7-Dihydroxycoumarin; Cichorigenin; Aesculetin; 6,7-Dihydroxy-2H-1-benzopyran-2-one; 6,7-Dihydroxy-2H-chromen-2-one; 2H-1-Benzopyran-2-one, 6,7-dihydroxy-
EINECS	261-945-1

Quality Control

Our 6,7-Dihydroxy-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to light and tendency for oxidation, it is recommended to handle under an inert atmosphere for long-term storage and to minimize headspace in opened containers.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	268°C - 272°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.