Description

Glabrol is a prenylated isoflavonoid compound, a key bioactive constituent derived from licorice root (Glycyrrhiza glabra). This high-purity compound is valued for its significant biological activity and serves as a critical reference standard and active ingredient. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, nutraceutical, and cosmetic industries for product development and quality control.

Application

• Pharmaceutical Research & Development: Used as a reference standard in analytical methods (HPLC, LC-MS) for the quantification of licorice-derived compounds in herbal extracts and finished products.
• Natural Product Isolation: Serves as a purified marker compound for the isolation and characterization of related flavonoids from botanical sources.
• Cosmetic & Skincare Formulations: Incorporated into formulations for its potential skin-brightening and anti-inflammatory properties, leveraging its tyrosinase inhibitory activity.
• Nutraceutical Supplements: Used as a standardized active ingredient in dietary supplements targeting antioxidant and wellness benefits.
• Biological Activity Studies: Employed in in vitro and in vivo research to investigate its pharmacological effects, including anti-inflammatory, antimicrobial, and hepatoprotective activities.
• Quality Control (QC) & Assurance: Essential for the identity and purity testing of licorice extracts to ensure batch-to-batch consistency and regulatory compliance.

Basic Information

Product Name	Glabrol
CAS No.	59870-65-4
Molecular Formula	C25H26O5
Molecular Weight	406.47 g/mol
Synonyms	4H-1-Benzopyran-4-one, 2,3-dihydro-7-hydroxy-2-(4-hydroxyphenyl)-8-(3-methyl-2-buten-1-yl)-5-[(E)-2-(4-hydroxyphenyl)ethenyl]-; 5-[(E)-2-(4-Hydroxyphenyl)ethenyl]-8-(3-methylbut-2-en-1-yl)-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one; 3''-Prenyl-2'',4'',4-trihydroxychalcone; Glabrone isomer; Licorice isoflavone B
EINECS	Contact for details

Quality Control

Our Glabrol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR, MS). We provide a Certificate of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or manufacturing requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.