Description

1-Bromo-3-Chloro-2-Nitrobenzene is a halogenated nitroaromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for constructing complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and material science industries seeking reliable and consistent raw materials for their processes.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug molecules, particularly those containing halogenated aromatic systems.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the nitro and halogen groups are pivotal for biological activity.
• Dye and Pigment Manufacturing: Acts as a precursor in the synthesis of specialized azo dyes and organic pigments.
• Material Science Research: Employed in the development of novel organic electronic materials and liquid crystals.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleophilic Aromatic Substitution: The nitro and halogen groups activate the benzene ring for substitution reactions, enabling further functionalization.

Basic Information

Product Name	1-Bromo-3-Chloro-2-Nitrobenzene
CAS No.	59772-48-4
Molecular Formula	C6H3BrClNO2
Molecular Weight	236.45 g/mol
Synonyms	2-Nitro-1-bromo-3-chlorobenzene; 3-Chloro-1-bromo-2-nitrobenzene; 1-Bromo-3-chloro-2-nitro-benzene; 2-Bromo-6-chloronitrobenzene; Benzene, 1-bromo-3-chloro-2-nitro-; o-Nitro-m-bromo-m-chlorobenzene; 3-Chloro-2-nitro-1-bromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-Chloro-2-Nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, GC, and NMR, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.