Description

2-Iodobenzyl Chloride is a versatile halogenated aromatic building block of significant importance in synthetic organic chemistry. Its primary value lies in its dual functionality, where the reactive benzyl chloride and aryl iodide groups serve as key handles for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and advanced intermediates through cross-coupling and substitution reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those requiring iodinated aromatic structures.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides where the iodine atom can be leveraged for further functionalization.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the creation of organic electronic materials and liquid crystals, where its halogen atoms facilitate molecular tuning and polymerization.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags for biochemical research and diagnostic applications.
• Custom Synthesis: A valuable reagent for contract research organizations (CROs) and fine chemical companies performing bespoke synthesis for clients.

Basic Information

Product Name	2-Iodobenzyl Chloride
CAS No.	59473-45-9
Molecular Formula	C7H6ClI
Molecular Weight	252.48 g/mol
Synonyms	1-(Chloromethyl)-2-iodobenzene; (2-Iodophenyl)methyl Chloride; α-Chloro-2-iodotoluene; o-Iodobenzyl Chloride; 2-Iodobenzylchloride; Benzene, 1-(chloromethyl)-2-iodo-; 2-Iodophenylchloromethane
EINECS	Contact for details

Quality Control

Our 2-Iodobenzyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of GMP and ISO standards for fine chemical production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and light-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.