Description

5-Chloro-1,2,3,4-Tetrahydronaphthalen-1-Amine is a versatile halogenated tetralin amine derivative that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure with a primary amine and chlorine substituent makes it a valuable intermediate for constructing complex molecules with specific pharmacological or material properties. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients or functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel central nervous system (CNS) agents, receptor modulators, and other bioactive molecules due to its tetralin scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Material Science Research: Serves as a precursor for dyes, pigments, and advanced polymers where the chlorinated aromatic amine structure imparts specific electronic or binding properties.
• Organic Chemistry Research: Employed as a model compound in methodological studies for cross-coupling reactions, amination, and ring-forming transformations.
• Ligand and Catalyst Development: The amine functionality allows for its use in creating chiral ligands or metal-organic complexes for catalytic applications.

Basic Information

Product Name	5-Chloro-1,2,3,4-Tetrahydronaphthalen-1-Amine
CAS No.	59376-81-7
Molecular Formula	C10H12ClN
Molecular Weight	181.66 g/mol
Synonyms	5-Chloro-1-amino-1,2,3,4-tetrahydronaphthalene; 5-Chloro-1,2,3,4-tetrahydro-1-naphthylamine; 1-Amino-5-chloro-1,2,3,4-tetrahydronaphthalene; 5-Chloro-α-tetralinamine; 5-Chloro-1-tetralinamine; 5-Chloro-1,2,3,4-tetrahydro-1-naphthalenamine; 5-Chloro-1,2,3,4-tetrahydronaphthalen-1-amine (primary name)
EINECS	Contact for details

Quality Control

Our 5-Chloro-1,2,3,4-Tetrahydronaphthalen-1-Amine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters to support your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.