Description

2-Thiophenecarboxylic Acid, 3-[[(1,1-Dimethylethyl)Amino]Sulfonyl]- is a specialized organosulfur compound featuring a thiophene backbone functionalized with a carboxylic acid and a tert-butylaminosulfonyl group. This unique molecular architecture makes it a valuable intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs) where specific steric and electronic properties are required. It is primarily sought by research and development chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to the thiophene moiety's bioisosteric properties.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the sulfonamide group can contribute to biological activity and environmental stability.
• Material Science Research: Serves as a precursor for functionalized polymers and organic electronic materials, leveraging the thiophene unit's conductive characteristics.
• Ligand and Catalyst Development: Employed in creating specialized ligands for metal catalysis or as a scaffold for organocatalysts in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design of molecular probes and inhibitors for studying enzyme function and signal transduction pathways.

Basic Information

Product Name	2-Thiophenecarboxylic Acid, 3-[[(1,1-Dimethylethyl)Amino]Sulfonyl]-
CAS No.	59337-98-3
Molecular Formula	C9H13NO4S2
Molecular Weight	263.33 g/mol
Synonyms	3-[(tert-Butylamino)sulfonyl]thiophene-2-carboxylic acid; 3-(N-tert-Butylsulfamoyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-[(1,1-dimethylethylamino)sulfonyl]-; 3-(tert-Butylsulfamoyl)thiophene-2-carboxylic acid; N-tert-Butyl-3-carboxythiophene-2-sulfonamide; 59337-98-3; tert-Butyl 3-carboxythiophene-2-sulfonamide
EINECS	Contact for details

Quality Control

Our production of 2-Thiophenecarboxylic Acid, 3-[[(1,1-Dimethylethyl)Amino]Sulfonyl]- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.