Description

2-Propen-1-One, 3-(Diethylamino)-2-Fluoro-1-Phenyl-, (Z)- (9Ci) is a specialized fluorinated enone building block featuring a unique combination of a diethylamino group and a fluorine atom on the α,β-unsaturated ketone scaffold. This compound matters for its role as a key intermediate in advanced organic synthesis, enabling the construction of complex molecules with precise stereochemistry and electronic properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas requiring fluorinated motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Advanced Material Research: Serves as a building block for creating specialized polymers, liquid crystals, or organic electronic materials that benefit from its specific molecular architecture.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes and tags for studying biological systems and enzyme mechanisms.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including asymmetric synthesis and the development of new fluorination or cross-coupling strategies.
• Fine Chemical Production: Utilized in custom synthesis and contract manufacturing for producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-Propen-1-One, 3-(Diethylamino)-2-Fluoro-1-Phenyl-, (Z)- (9Ci)
CAS No.	59160-23-5
Molecular Formula	C₁₃H₁₆FNO
Molecular Weight	221.27 g/mol
Synonyms	(Z)-3-(Diethylamino)-2-fluoro-1-phenyl-2-propen-1-one; 3-(Diethylamino)-2-fluoro-1-phenyl-2-propen-1-one, (Z)-; 2-Fluoro-3-(diethylamino)-1-phenyl-2-propen-1-one; (Z)-2-Fluoro-3-diethylamino-1-phenylpropenone; β-(Diethylamino)-α-fluorocinnamaldehyde; (Z)-β-(Diethylamino)-α-fluorocinnamaldehyde; (Z)-1-Phenyl-3-(diethylamino)-2-fluoroprop-2-en-1-one; 59160-23-5
EINECS	Contact for details

Quality Control

Our 2-Propen-1-One, 3-(Diethylamino)-2-Fluoro-1-Phenyl-, (Z)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our commitment to quality supports your R&D and scale-up processes with reliable, high-purity material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow solid or oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Typical 97-99%)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.