Description

2-Methoxyphenyl Trifluoromethanesulphonate is a high-purity organosulfur reagent featuring a reactive triflate leaving group. This compound is valued for its role as a versatile building block in advanced organic synthesis, particularly in cross-coupling reactions and the construction of complex molecular architectures. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing substituted aryl ether motifs.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides requiring specific aryl coupling steps.
• Material Science: Serves as a monomer or functionalization agent in the production of specialty polymers and advanced organic materials.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions such as Suzuki, Stille, and Negishi couplings due to the reactivity of the triflate group.
• Ligand and Catalyst Development: Employed in the preparation of novel phosphine ligands and organometallic catalysts.
• Chemical Research: A valuable tool in academic and industrial R&D for method development and exploring new synthetic pathways.

Basic Information

Product Name	2-Methoxyphenyl Trifluoromethanesulphonate
CAS No.	59099-58-0
Molecular Formula	C8H7F3O4S
Molecular Weight	256.20 g/mol
Synonyms	2-Methoxyphenyl Triflate; o-Methoxyphenyl Trifluoromethanesulfonate; (2-Methoxyphenyl) Trifluoromethanesulfonate; 2-Methoxy Phenyl Triflate; Trifluoromethanesulfonic Acid 2-Methoxyphenyl Ester; 2-Methoxy Phenyl Trifluoromethanesulphonate; 1-Methoxy-2-(trifluoromethanesulfonyloxy)benzene
EINECS	Contact for details

Quality Control

Every batch of 2-Methoxyphenyl Trifluoromethanesulphonate is manufactured and tested under a strict quality management system. We ensure compliance with relevant industry standards, and our quality protocols include rigorous analytical testing by HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and decomposition. Recommended storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.