Description

4-(2-Fluoro-Phenyl)-Piperazine-1-Carboxamidine is a high-purity, functionalized piperazine derivative of significant interest in advanced organic synthesis. This compound serves as a critical pharmacophore and versatile building block for the development of novel bioactive molecules. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in creating new therapeutic agents, particularly within the central nervous system (CNS) and receptor-targeted drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting serotonin, dopamine, and other neurotransmitter receptors.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Chemical Biology Probes: Employed in the development of labeled compounds and probes for studying enzyme mechanisms and protein-ligand interactions.
• Agrochemical Research: Serves as a building block for novel compounds with potential pesticidal or herbicidal activity.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for fundamental research in organic and medicinal chemistry.

Basic Information

Product Name	4-(2-Fluoro-Phenyl)-Piperazine-1-Carboxamidine
CAS No.	59083-58-8
Molecular Formula	C11H15FN4
Molecular Weight	222.26 g/mol
Synonyms	1-Carbamimidoyl-4-(2-fluorophenyl)piperazine; 4-(2-Fluorophenyl)piperazine-1-carboxamidine; 2-Fluorophenylpiperazine-1-carboxamidine; N-(2-Fluorophenyl)-N'-piperazinylformamidine; 59083-58-8; (2-Fluorophenyl)piperazine-1-carboxamidine; 1-(2-Fluorophenyl)-4-carbamimidoylpiperazine
EINECS	Contact for details

Quality Control

Our 4-(2-Fluoro-Phenyl)-Piperazine-1-Carboxamidine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, essential for sensitive research applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality commitment aligns with the standards expected for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.