Description

L-Isovaline, 4-(Methylthio)- (9Ci) is a specialized non-proteinogenic amino acid derivative characterized by its unique isovaline backbone modified with a methylthio group. This structural feature makes it a valuable chiral building block and intermediate for advanced research and synthesis. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for developing novel compounds and studying structure-activity relationships. Its specific stereochemistry and functional group offer precise control in synthetic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging its unique sulfur-containing side chain.
• Peptidomimetics & Bioactive Molecule Design: Acts as a constrained amino acid analog for creating peptide mimics with enhanced metabolic stability and bioavailability.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying enzyme mechanisms and receptor-ligand interactions.
• Asymmetric Synthesis Catalyst Ligand: Potential use as a precursor for chiral ligands or organocatalysts in enantioselective transformations.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-Isovaline, 4-(Methylthio)- (9Ci)
CAS No.	59013-75-1
Molecular Formula	C6H13NO2S
Molecular Weight	163.24 g/mol
Synonyms	(2S)-2-Amino-2-methyl-4-(methylthio)butanoic acid; L-2-Amino-2-methyl-4-(methylthio)butyric acid; 4-(Methylthio)-L-isovaline; (S)-2-Amino-2-methyl-4-(methylthio)butanoic acid; 4-Methylthio-L-isovaline; L-4-(Methylthio)isovaline; 59013-75-1; Butanoic acid, 2-amino-2-methyl-4-(methylthio)-, (2S)-
EINECS	Contact for details

Quality Control

Our L-Isovaline, 4-(Methylthio)- (9Ci) is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing specific results for all critical parameters are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent absorption of moisture, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.