Description

2-(Chloromethyl)-1-Methyl-4-Nitrobenzene is a versatile and high-purity organic intermediate of significant importance in advanced chemical synthesis. Its molecular structure, featuring both a reactive chloromethyl group and a nitro substituent, makes it a critical building block for constructing more complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), particularly those with complex aromatic backbones.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its nitro and chloromethyl functionalities are leveraged.
• Dye and Pigment Manufacturing: Serves as a building block for synthesizing specific azo dyes and other colored compounds.
• Organic Light-Emitting Diode (OLED) Materials: Acts as an intermediate in the creation of electron-transport or host materials for advanced display technologies.
• Liquid Crystal Intermediate: Utilized in the synthesis of certain liquid crystal molecules for electronic displays.
• Cross-Coupling Reactions: The chloromethyl group can be used in palladium-catalyzed cross-coupling reactions to form carbon-carbon bonds.
• Polymer Modification: Can be used to introduce functional groups into polymer chains for specialty plastics or resins.
• General Organic Synthesis: A valuable reagent in research laboratories for constructing nitro- and chloromethyl-substituted aromatic compounds.

Basic Information

Product Name	2-(Chloromethyl)-1-Methyl-4-Nitrobenzene
CAS No.	58966-24-8
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	4-Nitro-2-(chloromethyl)toluene; 2-Chloromethyl-4-nitrotoluene; 1-Methyl-2-(chloromethyl)-4-nitrobenzene; 2-Methyl-5-nitrobenzyl chloride; (4-Nitro-2-methylphenyl)methyl chloride; α-Chloro-4-nitro-o-xylene; NSC 403097
EINECS	Contact for details

Quality Control

Our 2-(Chloromethyl)-1-Methyl-4-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and reducing agents. The compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	64 - 68 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.