Description

(3S,6Aβ,10Bβ)-Dodecahydro-3,4Aα,7,7,10Aα-Pentamethyl-1H-Naphtho[2,1-B]Pyran-3β-Acetic Acid is a high-purity, complex tricyclic diterpenoid derivative with significant synthetic utility. This compound serves as a critical chiral intermediate and building block in advanced organic synthesis, valued for its defined stereochemistry and structural complexity. It is primarily sought after by research institutions and pharmaceutical development teams working on novel therapeutic agents, natural product synthesis, and specialized chemical libraries.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, particularly for complex small-molecule therapeutics.
• Natural Product Synthesis: Used as a sophisticated building block for the total or semi-synthesis of complex diterpenoid natural products and their analogs.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the construction of targeted molecular libraries for screening.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions due to its multiple stereogenic centers.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Chemical Biology Probes: Acts as a core structure for developing chemical probes to study biological pathways and protein functions.

Basic Information

Product Name	(3S,6Aβ,10Bβ)-Dodecahydro-3,4Aα,7,7,10Aα-Pentamethyl-1H-Naphtho[2,1-B]Pyran-3β-Acetic Acid
CAS No.	58917-30-9
Molecular Formula	C₂₂H₃₆O₃
Molecular Weight	348.52 g/mol
Synonyms	Labd-8(17)-en-15-oic acid, 13,14-didehydro-; 13,14-Didehydro-8(17)-labden-15-oic acid; (13E)-Labda-8(17),13-dien-15-oic acid; 8(17),13-Labdadien-15-oic acid; Copalic acid derivative; Diterpenoid acid intermediate; Tricyclic diterpene acid
EINECS	Contact for details

Quality Control

Our (3S,6Aβ,10Bβ)-Dodecahydro-3,4Aα,7,7,10Aα-Pentamethyl-1H-Naphtho[2,1-B]Pyran-3β-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is compatible with strong acids and organic solvents but should be stored away from incompatible materials. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.