Description

2-(4-Chlorophenyl)-α-Methyl-7-Benzoxazoleacetic Acid is a high-purity, non-steroidal anti-inflammatory drug (NSAID) intermediate of significant commercial and research interest. This compound is a critical building block in the synthesis of advanced pharmaceutical agents, particularly those targeting inflammation and pain. It is primarily required by manufacturers and R&D laboratories in the pharmaceutical and fine chemical sectors for the development of new therapeutic molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potent NSAIDs and other bioactive molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of novel anti-inflammatory agents.
• Fine Chemical Synthesis: Serves as a versatile building block for constructing complex heterocyclic compounds in custom synthesis projects.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	2-(4-Chlorophenyl)-α-Methyl-7-Benzoxazoleacetic Acid
CAS No.	58902-62-8
Molecular Formula	C₁₆H₁₂ClNO₃
Molecular Weight	301.72 g/mol
Synonyms	2-(p-Chlorophenyl)-α-methyl-7-benzoxazoleacetic acid; 2-(4-Chlorophenyl)-α-methyl-1,3-benzoxazole-7-acetic acid; 7-Benzoxazoleacetic acid, 2-(4-chlorophenyl)-α-methyl-; Loxoprofen Impurity; Loxoprofen Related Compound; Felbinac Intermediate; Felbinac Derivative; Oxaprozin Intermediate
EINECS	Contact for details

Quality Control

Our 2-(4-Chlorophenyl)-α-Methyl-7-Benzoxazoleacetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥98% by HPLC), related substances, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.