Description

trans-n-p-Tolylsulfonyl-1,2-Diaminocyclohexane is a high-purity, chiral diamine derivative featuring a tosyl-protected amine group. This compound serves as a critical chiral building block and ligand precursor in asymmetric synthesis, valued for its ability to impart stereoselectivity in catalytic reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries developing enantiomerically pure active ingredients and advanced intermediates.

Application

• Asymmetric Catalysis: As a precursor for chiral ligands and catalysts used in hydrogenation, epoxidation, and other stereoselective transformations.
• Pharmaceutical Intermediates: In the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for central nervous system and cardiovascular drugs.
• Agrochemical Synthesis: For creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Chiral Resolution Agent: Used to separate racemic mixtures of acids or other compounds via diastereomeric salt formation.
• Fine Chemical Building Block: In the multi-step synthesis of complex, high-value specialty chemicals requiring defined stereochemistry.
• Academic & Industrial Research: As a standard reagent in method development for new asymmetric synthetic pathways.

Basic Information

Product Name	trans-n-p-Tolylsulfonyl-1,2-Diaminocyclohexane
CAS No.	58825-94-8
Molecular Formula	C13H20N2O2S
Molecular Weight	268.37 g/mol
Synonyms	(1R,2R)-N-(4-Methylphenyl)sulfonyl-1,2-cyclohexanediamine; (1R,2R)-(-)-1,2-Diaminocyclohexane N,N'-bis(p-toluenesulfonamide); trans-1,2-Diaminocyclohexane-N-p-toluenesulfonamide; (R,R)-TsDACH; (1R,2R)-N-(p-Tolylsulfonyl)-1,2-diaminocyclohexane; (R,R)-DACH-Ts; trans-N-(p-Toluenesulfonyl)-1,2-diaminocyclohexane
EINECS	Contact for details

Quality Control

Our trans-n-p-Tolylsulfonyl-1,2-Diaminocyclohexane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and enantiomeric excess meet the highest standards for research and industrial use. A detailed Certificate of Analysis (COA) providing specifications for assay, chiral purity, and related substances is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.