Description

4(S)-Amino-Chroman-3(S)-Ol is a high-purity chiral intermediate of significant importance in asymmetric synthesis. This compound is valued for its stereochemically defined structure, which is crucial for imparting specific biological activity in advanced pharmaceutical compounds. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active pharmaceutical ingredients (APIs) and complex organic molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Asymmetric Synthesis: Used as a precursor or catalyst ligand in stereoselective reactions to create enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals requiring specific stereochemistry.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D for methodological studies in organic and medicinal chemistry.
• Agrochemical Synthesis: Potential intermediate in the development of chiral active ingredients for crop protection products.

Basic Information

Product Name	4(S)-Amino-Chroman-3(S)-Ol
CAS No.	58810-67-6
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(3S,4S)-4-Amino-3,4-dihydro-2H-chromen-3-ol; (3S,4S)-4-Amino-3,4-dihydro-2H-1-benzopyran-3-ol; 4-Amino-3,4-dihydro-2H-1-benzopyran-3-ol (S,S)-isomer; (S,S)-4-Aminochroman-3-ol; 4-Aminochroman-3-ol; Chroman-3-ol, 4-amino-, (3S,4S)-; 58810-67-6
EINECS	Contact for details

Quality Control

Our 4(S)-Amino-Chroman-3(S)-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity and chemical identity verification, to ensure it meets the stringent requirements for pharmaceutical-grade intermediates. A Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.