Description

(1α,3α,5α)-5-Methyl-1,3-Bis(Trimethylsiloxy)Cyclohexane is a specialized organosilicon compound featuring a cyclohexane backbone with two trimethylsiloxy protecting groups. This structure is critical for its role as a versatile intermediate and protecting group reagent in advanced organic synthesis. It is particularly valuable for industries requiring precise control over molecular architecture and functional group manipulation. Key sectors that utilize this compound include pharmaceutical development, agrochemical research, and the synthesis of specialty materials.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of complex drug molecules, particularly where steric protection of hydroxyl groups is required.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its stability and reactivity in multi-step syntheses.
• Silicon-Based Polymer Research: Acts as a monomer or modifying agent in the development of novel silicone resins and hybrid organic-inorganic materials.
• Organic Synthesis Reagent: Functions as a protecting group for diols or as a silylating agent in laboratory-scale and pilot-plant reactions.
• Flavor & Fragrance Industry: Employed in the synthesis of certain terpene-derived aroma chemicals and musk compounds.
• Material Science: Investigated for use in surface modification, coatings, and as a precursor for advanced ceramic materials.

Basic Information

Product Name	(1α,3α,5α)-5-Methyl-1,3-Bis(Trimethylsiloxy)Cyclohexane
CAS No.	58800-82-1
Molecular Formula	C13H30O2Si2
Molecular Weight	274.55 g/mol
Synonyms	5-Methyl-1,3-bis(trimethylsiloxy)cyclohexane; 1,3-Bis-O-(trimethylsilyl)-5-methylcyclohexane-1,3-diol; 5-Methylcyclohexane-1,3-diyl bis(trimethylsilyl) ether; Cyclohexane, 5-methyl-1,3-bis[(trimethylsilyl)oxy]-; TMS-protected 5-methylcyclohexane-1,3-diol; 1,3-Di-O-trimethylsilyl-5-methylcyclohexane-1,3-diol; (1alpha,3alpha,5alpha)-5-Methyl-1,3-bis(trimethylsiloxy)cyclohexane
EINECS	Contact for details

Quality Control

Our (1α,3α,5α)-5-Methyl-1,3-Bis(Trimethylsiloxy)Cyclohexane is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP guidelines where applicable. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and can tailor specifications to meet specific project requirements, including compliance with relevant pharmacopeial standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC or HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.