Description

(S)-2,3-Dihydro-5,7-Dihydroxy-6-[(2-Hydroxyphenyl)Methyl]-2-Phenyl-4H-1-Benzopyran-4-One CAS NO 58777-17-6 is a high-purity, chiral flavanone derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a sophisticated chiral building block and a potential pharmacophore for developing novel therapeutic agents. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for applications in asymmetric synthesis and medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of complex bioactive molecules and potential drug candidates.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in stereoselective chemical reactions to create enantiomerically pure compounds.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and library synthesis for screening against various biological targets.
• Natural Product Analog Synthesis: Used to create synthetic analogs of naturally occurring flavanones for biological evaluation.
• Biochemical Tool Compound: Acts as a standard or probe in enzymatic and receptor binding assays within academic and industrial research settings.
• Fine Chemical Production: Incorporated into the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	(S)-2,3-Dihydro-5,7-Dihydroxy-6-[(2-Hydroxyphenyl)Methyl]-2-Phenyl-4H-1-Benzopyran-4-One
CAS No.	58777-17-6
Molecular Formula	C22H18O5
Molecular Weight	362.38 g/mol
Synonyms	(S)-6-(2-Hydroxybenzyl)-5,7-dihydroxy-2-phenylchroman-4-one; (S)-5,7-Dihydroxy-6-(2-hydroxybenzyl)-2-phenylchroman-4-one; (S)-Sophoraflavanone G; (S)-Lupinifolin; (S)-2,3-Dihydro-5,7-dihydroxy-2-phenyl-6-(2-hydroxybenzyl)-4H-1-benzopyran-4-one; (S)-Flavanone derivative 58777-17-6; (S)-6-(2-Hydroxybenzyl)-5,7-dihydroxyflavanone
EINECS	Contact for details

Quality Control

Our (S)-2,3-Dihydro-5,7-Dihydroxy-6-[(2-Hydroxyphenyl)Methyl]-2-Phenyl-4H-1-Benzopyran-4-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); for long-term storage, consider packaging under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	Off-white to pale yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (S-enantiomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.