Description

2-(4-Chloro-Phenyl)-Succinic Acid is a versatile chlorinated succinic acid derivative, serving as a key chiral building block and intermediate in advanced organic synthesis. Its value lies in its bifunctional structure, which allows for selective chemical modifications to create complex molecules with high stereochemical purity. This compound is essential for research and production in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of chiral active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators, leveraging its chlorophenyl moiety for biological activity.
• Liquid Crystal & Polymer Chemistry: Acts as a monomer or modifying agent in the synthesis of specialty polymers and liquid crystal materials for electronic displays.
• Chiral Resolving Agent: Employed in the separation of racemic mixtures due to its inherent chirality, aiding in the production of enantiomerically pure compounds.
• Organic Synthesis Building Block: Utilized in various name reactions and coupling processes to construct more complex molecular architectures in research and development.
• Dye & Pigment Intermediate: Serves as a starting material for synthesizing specialized dyes and pigments with specific color fastness and stability properties.

Basic Information

Product Name	2-(4-Chloro-Phenyl)-Succinic Acid
CAS No.	58755-91-2
Molecular Formula	C10H9ClO4
Molecular Weight	228.63 g/mol
Synonyms	(4-Chlorophenyl)succinic Acid; 2-(p-Chlorophenyl)succinic Acid; 4-Chloro-α-(carboxymethyl)benzenepropanoic Acid; 2-(4-Chlorophenyl)butanedioic Acid; p-Chlorophenylsuccinic Acid; 58755-91-2; 2-(4-Chlorophenyl)-1,4-butanedioic Acid
EINECS	Contact for details

Quality Control

Our 2-(4-Chloro-Phenyl)-Succinic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral assays, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) are provided with every shipment, detailing all specified parameters. We adhere to cGMP principles where applicable to guarantee supply reliability and batch-to-batch consistency for our global customers.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent absorption of atmospheric moisture, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (enantiomeric excess)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.