Description

Cyclobutane-1α,2β-Dicarboxylic Acid CAS NO 58616-97-0 is a high-purity, functionalized cyclobutane derivative serving as a critical chiral building block in advanced organic synthesis. This compound matters for its rigid, strained four-membered ring structure, which is highly valuable for constructing complex molecular architectures with precise stereochemistry. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in antiviral and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of polymers and advanced materials with unique thermal or mechanical properties derived from the cyclobutane scaffold.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening and functionalization reactions.

Basic Information

Product Name	Cyclobutane-1α,2β-Dicarboxylic Acid
CAS No.	58616-97-0
Molecular Formula	C6H8O4
Molecular Weight	144.13 g/mol
Synonyms	(1R,2S)-Cyclobutane-1,2-dicarboxylic Acid; (1α,2β)-1,2-Cyclobutanedicarboxylic Acid; trans-(1R,2S)-Cyclobutane-1,2-dicarboxylic Acid; 1,2-Cyclobutanedicarboxylic Acid, (1R,2S)-rel-; NSC 163080; Cyclobutane-1,2-dicarboxylic acid, (1R,2S)-; (1R,2S)-rel-1,2-Cyclobutanedicarboxylic Acid
EINECS	Contact for details

Quality Control

Our Cyclobutane-1α,2β-Dicarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.