Description

4-tert-Butyl-2,6-Dimethylbenzoic Acid is a sterically hindered benzoic acid derivative characterized by its unique substitution pattern. This compound serves as a valuable advanced intermediate in the synthesis of complex organic molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development teams for constructing molecules where its bulky, lipophilic tert-butyl group and carboxylic acid functionality are critical for imparting specific biological activity or material properties.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its structural motif contributes to efficacy and environmental stability.
• Liquid Crystal & Polymer Additive: Acts as a monomer or a modifying agent in the production of specialty polymers and liquid crystal materials, influencing thermal and optical properties.
• Organic Synthesis Reagent: Employed in academic and industrial research as a precursor for metal-organic frameworks (MOFs), ligands for catalysis, and in the development of novel chemical entities.
• Fine Chemical Production: Serves as an intermediate for dyes, pigments, and other performance chemicals requiring a sterically hindered aromatic acid component.

Basic Information

Product Name	4-tert-Butyl-2,6-Dimethylbenzoic Acid
CAS No.	58537-98-7
Molecular Formula	C13H18O2
Molecular Weight	206.28 g/mol
Synonyms	2,6-Dimethyl-4-tert-butylbenzoic Acid; Benzoic acid, 4-(1,1-dimethylethyl)-2,6-dimethyl-; 4-(tert-Butyl)-2,6-dimethylbenzoic Acid; 4-tert-Butyl-2,6-dimethyl-benzoic acid; 4-(1,1-Dimethylethyl)-2,6-dimethylbenzoic Acid; 2,6-Dimethyl-4-(tert-butyl)benzoic Acid; 4-tert-Butyl-2,6-dimethylbenzoic acid (predominant)
EINECS	Contact for details

Quality Control

Our production of 4-tert-Butyl-2,6-Dimethylbenzoic Acid adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and specific impurity profiles is provided with each shipment. We support cGMP and ISO 9001 compliant manufacturing practices for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to minimize exposure to atmospheric humidity. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.