Description

3-(3-Chloro-4-Fluorophenyl)Prop-2-Enoic Acid, also known as 3-(3-Chloro-4-Fluorophenyl)Acrylic Acid, is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique halogenated structure enables precise molecular modifications. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anti-inflammatory agent research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and fungicides, leveraging the bioactivity of the chloro-fluorophenyl moiety.
• Liquid Crystal Materials: Serves as a building block for fluorinated liquid crystal compounds used in display technologies.
• Organic Light-Emitting Diodes (OLEDs): Employed in the synthesis of electron-transport or emissive layer materials for electronic devices.
• Polymer Modification: Acts as a monomer or cross-linking agent for introducing aromatic and halogenated functionalities into specialty polymers.
• Chemical Research & Development: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions in medicinal and materials chemistry.

Basic Information

Product Name	3-(3-Chloro-4-Fluorophenyl)Prop-2-Enoic Acid / 3-(3-Chloro-4-Fluorophenyl)Acrylic Acid
CAS No.	58537-11-4
Molecular Formula	C9H6ClFO2
Molecular Weight	200.59 g/mol
Synonyms	(E)-3-(3-Chloro-4-fluorophenyl)acrylic acid; 3-(3-Chloro-4-fluorophenyl)-2-propenoic acid; trans-3-(3-Chloro-4-fluorocinnamic acid); 3-Chloro-4-fluorocinnamic acid; 3-(3-Chloro-4-fluorophenyl)propenoic acid; 58537-11-4; 3-(3-Chloro-4-fluorophenyl)acrylicacid
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-4-Fluorophenyl)Acrylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.