Description

2-Bromo-5-Hydroxybenzoic Acid is a versatile halogenated hydroxybenzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and phenolic hydroxyl groups, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and other crop protection agents where the bromine substituent enhances biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its functional groups that can be further modified.
• Dye and Pigment Intermediate: Acts as a building block for synthesizing complex dyes and organic pigments, leveraging the reactivity of the bromine atom.
• Custom Synthesis and Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecular targets.

Basic Information

Product Name	2-Bromo-5-Hydroxybenzoic Acid
CAS No.	58380-11-3
Molecular Formula	C7H5BrO3
Molecular Weight	217.02 g/mol
Synonyms	5-Hydroxy-2-bromobenzoic Acid; 2-Bromo-5-hydroxybenzoic acid; 2-Bromo-5-salicylic acid; Benzoic acid, 2-bromo-5-hydroxy-; 58380-11-3; 2-Br-5-OH-BA
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Hydroxybenzoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	205 - 210 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.