Description

[1R-(1Alpha,2Beta,3Alpha,5Alpha)]-2,6,6-Trimethylbicyclo[3.1.1]heptane-3-carboxylic acid is a high-purity, stereochemically defined terpenoid carboxylic acid. This compound is a key chiral synthon and intermediate valued for its rigid bicyclic structure and defined stereochemistry, which are critical for synthesizing complex molecules with specific biological activity. It is essential for research and development in the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of terpene-based therapeutics and fragrances.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging its complex bicyclic structure for bioactivity.
• Fine Chemical Production: Serves as a precursor for high-value flavors, fragrances, and other specialty chemicals requiring a defined pinane skeleton.
• Asymmetric Catalysis Research: Employed as a chiral auxiliary or ligand precursor in academic and industrial research to study and develop new stereoselective reactions.
• Material Science: Investigated as a monomer or additive for creating novel polymers with specific thermal or optical properties derived from its rigid structure.

Basic Information

Product Name	[1R-(1Alpha,2Beta,3Alpha,5Alpha)]-2,6,6-Trimethylbicyclo[3.1.1]heptane-3-carboxylic Acid
CAS No.	58096-29-0
Molecular Formula	C11H18O2
Molecular Weight	182.26 g/mol
Synonyms	(1R,2S,3R,5S)-3-Pinancarboxylic Acid; (1R,2S,3R,5S)-Pinane-3-carboxylic Acid; (-)-Pinonic Acid (specific enantiomer); 3-Carboxy-(1R,2S,3R,5S)-pinane; (1R,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-3-carboxylic Acid; Bicyclo[3.1.1]heptane-3-carboxylic acid, 2,6,6-trimethyl-, (1R,2S,3R,5S)-
EINECS	Contact for details

Quality Control

Our [1R-(1Alpha,2Beta,3Alpha,5Alpha)]-2,6,6-Trimethylbicyclo[3.1.1]heptane-3-carboxylic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets exacting standards for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.