Description

(R)-(+)-3-Hydroxybutyrolactone is a high-purity chiral building block and versatile intermediate in organic synthesis. This compound matters for its critical role in the production of optically active pharmaceuticals and fine chemicals, where its specific stereochemistry is essential for biological activity and process efficiency. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis for creating advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of statin drugs (e.g., Atorvastatin, Rosuvastatin) and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for flavors, fragrances, and advanced polymer monomers.
• Biochemical Research: Employed in studies of metabolic pathways and as a precursor for biochemical probes.
• Asymmetric Catalysis: Utilized as a ligand or a substrate in catalytic reactions to induce chirality.
• Material Science: A monomer for synthesizing biodegradable polymers and specialty polyesters.

Basic Information

Product Name	(R)-(+)-3-Hydroxybutyrolactone
CAS No.	58081-05-3
Molecular Formula	C4H6O3
Molecular Weight	102.09 g/mol
Synonyms	(R)-(+)-γ-Hydroxybutyrolactone; (R)-3-Hydroxy-dihydro-2(3H)-furanone; (R)-Pantolactone; D-(+)-Pantolactone; (R)-4-Hydroxybutyric acid γ-lactone; (3R)-3,4-Dihydroxybutanoic acid lactone; (R)-3-Hydroxybutyrolactone; (R)-Tetrahydro-2-oxo-3-furanol
EINECS	Contact for details

Quality Control

Our (R)-(+)-3-Hydroxybutyrolactone is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and advanced synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed after opening to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.