Description

2-Bromo-4-(Trifluoromethyl)Aniline is a high-purity, halogenated aniline derivative serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of bromine and trifluoromethyl substituents, which are essential for modulating the electronic and steric properties of target molecules. This compound is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a precursor for functional dyes, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Chemical Research: Employed in academic and industrial labs for exploring new synthetic methodologies and creating complex molecular architectures.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Aniline
CAS No.	57946-63-1
Molecular Formula	C7H5BrF3N
Molecular Weight	240.02 g/mol
Synonyms	2-Bromo-4-(trifluoromethyl)benzenamine; 2-Bromo-α,α,α-trifluoro-p-toluidine; 2-Bromo-4-trifluoromethylaniline; 4-Amino-3-bromobenzotrifluoride; Benzenamine, 2-bromo-4-(trifluoromethyl)-; 2-Bromo-4-trifluoromethylphenylamine; 3-Bromo-4-aminobenzotrifluoride; 2-Bromo-α,α,α-trifluoro-4-methylaniline
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.