Description

Benzene, 1-Cyclopropyl-4-Iodo- is a specialized halogenated aromatic building block of significant interest in advanced organic synthesis. This compound, with CAS number 57807-27-9, is valued for its unique structural motif combining a cyclopropyl group with an iodine substituent on a benzene ring, enabling precise molecular construction. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the cyclopropyl moiety for bioactivity.
• Material Science: Serves as a building block for advanced organic electronic materials, such as charge-transport molecules and liquid crystals.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Sonogashira couplings for carbon-carbon bond formation.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a core structure for developing molecular probes and tags used in biochemical assays and imaging.

Basic Information

Product Name	Benzene, 1-Cyclopropyl-4-Iodo-
CAS No.	57807-27-9
Molecular Formula	C9H9I
Molecular Weight	244.07 g/mol
Synonyms	1-Cyclopropyl-4-iodobenzene; 4-Iodocyclopropylbenzene; (4-Iodophenyl)cyclopropane; p-Iodocyclopropylbenzene; 1-Iodo-4-cyclopropylbenzene; Cyclopropyl-4-iodobenzene; Benzene, cyclopropyl-4-iodo-; 57807-27-9 (CAS)
EINECS	Contact for details

Quality Control

Every batch of 1-Cyclopropyl-4-iodobenzene is produced and analyzed under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as identity, assay, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for traceability and reliability, making this material suitable for demanding synthetic campaigns.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.