Description

1-[(1S,3R)-3-Bromo-1,2,2-Trimethylcyclopentyl]-4-Methylbenzene is a high-purity, stereochemically defined brominated aromatic compound with a complex cyclopentane backbone. This structural complexity makes it a valuable and versatile chiral building block for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty materials. It is primarily sought by research and development chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular architecture for their synthetic routes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and synthesis of novel therapeutic agents, including potential central nervous system (CNS) drugs and anti-inflammatory compounds.
• Agrochemical Research: Used in the development of new, more effective pesticides and herbicides where specific stereochemistry can influence biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Investigated as a monomer or additive for creating polymers and liquid crystals with unique optical or mechanical properties.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, exploring new bromination and cross-coupling reactions.
• Fragrance & Flavor Chemistry: Potential use as an intermediate for synthesizing complex, musky, or woody aroma chemicals due to its substituted benzene and terpene-like structure.

Basic Information

Product Name	1-[(1S,3R)-3-Bromo-1,2,2-Trimethylcyclopentyl]-4-Methylbenzene
CAS No.	57794-64-6
Molecular Formula	C₁₅H₂₁Br
Molecular Weight	281.23 g/mol
Synonyms	(1S,3R)-3-Bromo-1,2,2-trimethyl-1-(4-methylphenyl)cyclopentane; 1-[(1S,3R)-3-Bromo-1,2,2-trimethylcyclopentyl]-4-methylbenzene; p-Methyl-1-[(1S,3R)-3-bromo-1,2,2-trimethylcyclopentyl]benzene; (1S,3R)-1-(4-Methylphenyl)-3-bromo-1,2,2-trimethylcyclopentane; Bromo-trimethylcyclopentyl-methylbenzene (stereoisomer); CAS 57794-64-6
EINECS	Contact for details

Quality Control

Every batch of 1-[(1S,3R)-3-Bromo-1,2,2-Trimethylcyclopentyl]-4-Methylbenzene is produced and analyzed under strict quality management protocols. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure high chiral purity and chemical identity. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.