Description

5-Hydroxy-2-Iodobenzoic Acid is a halogenated benzoic acid derivative that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a phenolic hydroxyl and an iodine substituent, makes it a critical building block for constructing complex molecules with high precision. This compound is primarily utilized by research institutions and pharmaceutical developers engaged in the synthesis of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry research for developing targeted therapies.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators due to its reactive halogen site.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials where its iodine group facilitates further cross-coupling reactions.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecular probes and tags for studying biological systems.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	5-Hydroxy-2-Iodobenzoic Acid
CAS No.	57772-57-3
Molecular Formula	C7H5IO3
Molecular Weight	263.02 g/mol
Synonyms	2-Iodo-5-hydroxybenzoic acid; 5-Hydroxy-2-iodobenzoic acid; 2-Iodosalicylic acid; 5-Hydroxy-o-iodobenzoic acid; Benzoic acid, 5-hydroxy-2-iodo-; o-Iodo-5-hydroxybenzoic acid; 5-Hydroxy-2-iodobenzoic acid (CAS 57772-57-3)
EINECS	Contact for details

Quality Control

Our 5-Hydroxy-2-Iodobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.