Description

Sodium 2-Hydroxy-3-Methylbutyrate is the sodium salt of the branched-chain hydroxy acid, 2-hydroxy-3-methylbutyric acid. This compound serves as a stable and bioavailable source of the metabolite HMB (β-hydroxy β-methylbutyrate), which is critical for supporting protein synthesis and reducing muscle breakdown. It is primarily utilized by manufacturers in the sports nutrition, clinical nutrition, and functional food and beverage sectors seeking to fortify products with evidence-based ergogenic and anti-catabolic ingredients.

Application

• Sports Nutrition & Dietary Supplements: A key active ingredient in powders, capsules, and ready-to-drink formulations aimed at enhancing muscle recovery, strength, and lean mass gains.
• Clinical & Medical Nutrition: Used in specialized enteral and parenteral nutrition products to help mitigate muscle wasting in critically ill, elderly, or cachexic patients.
• Functional Food & Beverage Fortification: Incorporated into protein bars, shakes, meal replacements, and other fortified foods to provide added nutritional benefits.
• Animal Feed & Veterinary Applications: Employed in premium livestock and companion animal feed to promote growth performance, feed efficiency, and overall health.
• Pharmaceutical Intermediates: Serves as a valuable chiral building block or intermediate in the synthesis of more complex pharmaceutical compounds.
• Cosmeceutical Formulations: Explored for use in skincare products for its potential role in supporting skin health and integrity.

Basic Information

Product Name	Sodium 2-Hydroxy-3-Methylbutyrate
CAS No.	57768-96-4
Molecular Formula	C5H9NaO3
Molecular Weight	140.11 g/mol
Synonyms	Sodium HMB; HMB-Ca; β-Hydroxy β-Methylbutyrate Sodium Salt; Calcium β-hydroxy-β-methylbutyrate (common trade form); 3-Hydroxy-3-methylbutanoic acid sodium salt; 2-Hydroxy-3-methylbutyric acid sodium salt; HMB Monohydrate (common form); (R,S)-3-Hydroxy-3-methylbutyrate sodium salt
EINECS	Contact for details

Quality Control

Our Sodium 2-Hydroxy-3-Methylbutyrate is manufactured under a cGMP-compliant quality system to ensure consistency and purity suitable for human consumption. Each batch is rigorously tested against stringent internal specifications. A comprehensive Certificate of Analysis (COA) documenting identity, purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the original container must be kept tightly sealed after use to prevent absorption of atmospheric moisture which can lead to caking or degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Microbiological Analysis	Meets standard requirements for dietary ingredients

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.