Description

(1R)-1β-Bromo-4α,5α-Dichloro-2α-[(E)-2-Chloroethenyl]-1,5-Dimethylcyclohexane is a high-purity, stereochemically defined halogenated cyclohexane derivative, serving as a critical chiral building block and advanced intermediate in complex organic syntheses. Its precise molecular architecture, featuring multiple halogen substituents and a defined stereocenter, makes it invaluable for constructing pharmacologically active molecules and specialty materials. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality intermediates for innovative synthesis.

Application

• Pharmaceutical Intermediate: Key chiral precursor for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-infective drug discovery.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where its halogenated structure contributes to biological activity.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and liquid crystals.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and exploring new chemical spaces via cross-coupling and cyclization reactions.
• Catalyst & Ligand Development: Potential precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	(1R)-1β-Bromo-4α,5α-Dichloro-2α-[(E)-2-Chloroethenyl]-1,5-Dimethylcyclohexane
CAS No.	57566-88-8
Molecular Formula	C10H14BrCl3
Molecular Weight	312.48 g/mol
Synonyms	(1R,2S,4R,5S)-1-Bromo-4,5-dichloro-2-[(E)-2-chloroethenyl]-1,5-dimethylcyclohexane; (1R)-1β-Bromo-4α,5α-dichloro-2α-[(E)-2-chloroethenyl]-1,5-dimethylcyclohexane; rel-(1R,2S,4R,5S)-1-Bromo-4,5-dichloro-2-[(1E)-2-chloroethenyl]-1,5-dimethylcyclohexane; 1-Bromo-4,5-dichloro-2-(2-chlorovinyl)-1,5-dimethylcyclohexane (stereoisomer); Halogenated Cyclohexane Derivative 57566-88-8; BDDC Intermediate
EINECS	Contact for details

Quality Control

Every batch of (1R)-1β-Bromo-4α,5α-Dichloro-2α-[(E)-2-Chloroethenyl]-1,5-Dimethylcyclohexane is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC, NMR, and GC-MS, to ensure identity, purity, and stereochemical integrity meet the stringent requirements of advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to guarantee supply reliability and batch-to-batch consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light) and should be kept under an inert atmosphere for long-term storage to preserve stability. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.