Description

4'-Iodobiphenyl-3-Carboxylic Acid is a high-purity iodinated biphenyl derivative that serves as a versatile and critical building block in advanced organic synthesis. Its molecular structure, featuring both a carboxylic acid group and an iodine atom on a biphenyl scaffold, makes it an essential intermediate for constructing complex molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly in medicinal chemistry and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially for non-steroidal anti-inflammatory drugs (NSAIDs) and other bioactive molecules.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis, including those for cross-coupling reactions like Suzuki-Miyaura and Buchwald-Hartwig amination.
• Liquid Crystal & OLED Materials: Serves as a core component in the research and production of advanced organic electronic materials, such as liquid crystal displays (LCDs) and organic light-emitting diodes (OLEDs).
• Agrochemical Research: Intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Polymer Modification: Employed to introduce functional groups into polymer backbones to alter physical properties like thermal stability and solubility.
• Chemical Biology Probes: Useful for creating tagged molecules and probes for studying biological pathways and protein interactions.

Basic Information

Product Name	4'-Iodobiphenyl-3-Carboxylic Acid
CAS No.	57498-62-1
Molecular Formula	C13H9IO2
Molecular Weight	324.12 g/mol
Synonyms	3-(4-Iodophenyl)benzoic acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-iodo-; 4'-Iodo-1,1'-biphenyl-3-carboxylic acid; 4-Iodobiphenyl-3-carboxylic Acid; 3-Carboxy-4'-iodobiphenyl; Biphenyl-3-carboxylic acid, 4'-iodo-; 4'-Iodo-[1,1'-biphenyl]-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4'-Iodobiphenyl-3-Carboxylic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting critical parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.