Description

D-Praziquantel is the dextrorotatory enantiomer of the anthelmintic compound praziquantel, representing a high-purity, single-isomer active pharmaceutical ingredient (API). This specific stereochemistry is critical for targeted research and development in advanced pharmaceutical formulations. It is essential for manufacturers and research institutions focused on developing and producing enantiomerically pure antiparasitic treatments. The compound is supplied under stringent quality control to meet the exacting standards of the global pharmaceutical and life science sectors.

Application

• Pharmaceutical API: Primary use as the active enantiomer in the synthesis of advanced anthelmintic drugs targeting trematode and cestode infections.
• Veterinary Medicine: Key ingredient in formulations for treating parasitic worm infections in livestock and companion animals.
• Research & Development: Critical reference standard and building block in medicinal chemistry for studying structure-activity relationships and developing new antiparasitic agents.
• Analytical Standards: Used as a high-purity calibrant in HPLC, LC-MS, and other analytical methods for quality control and regulatory testing.
• Process Chemistry: Serves as an intermediate in the asymmetric synthesis of complex pharmaceutical molecules.

Basic Information

Product Name	D-Praziquantel
CAS No.	57452-97-8
Molecular Formula	C19H24N2O2
Molecular Weight	312.41 g/mol
Synonyms	(R)-Praziquantel; Dextro-Praziquantel; (11bR)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; Praziquantel D-isomer; D-PZQ; (R)-2-(Cyclohexylcarbonyl)-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinolin-4-one; Biltricide (D-enantiomer)
EINECS	Contact for details

Quality Control

Our D-Praziquantel is manufactured under strict quality management systems. Every batch is tested to ensure it meets high-purity standards, with typical specifications focusing on enantiomeric excess (ee), chemical purity, and the control of related substances. Certificates of Analysis (COA) detailing results for identity, assay, impurities, and residual solvents are provided with each shipment. We support compliance with ICH Q7 guidelines and can tailor quality attributes to meet specific pharmacopeial or customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.