Description

[(4-Methoxybenzoyl)Thio]Acetic Acid is a specialized organosulfur compound featuring a thioester linkage to an acetic acid moiety. This molecular architecture makes it a valuable building block and intermediate in advanced organic synthesis, particularly for constructing complex molecules with specific functional groups. It is primarily utilized by pharmaceutical R&D and fine chemical manufacturers for applications requiring precise molecular modification.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thioester or modified benzoic acid structures.
• Peptide Mimetics & Conjugation: Used in the development of peptide analogs and for bioconjugation strategies, leveraging its reactive thioester group.
• Ligand Synthesis for Catalysis: Serves as a starting material for creating specialized ligands used in transition metal catalysis.
• Material Science Research: Employed in the synthesis of novel monomers or functional agents for advanced polymers and organic electronic materials.
• Agrochemical Development: Intermediate in the research and production of new generation herbicides or plant growth regulators.
• Chemical Biology Probes: Useful for synthesizing probes that target specific enzymatic activity or for protein labeling studies.

Basic Information

Product Name	[(4-Methoxybenzoyl)Thio]Acetic Acid
CAS No.	57436-45-0
Molecular Formula	C10H10O4S
Molecular Weight	226.25 g/mol
Synonyms	4-Methoxybenzoylthioacetic Acid; (4-Methoxybenzoylthio)acetic Acid; [(4-Methoxyphenyl)carbonothioyl]acetic Acid; p-Methoxybenzoylthioacetic Acid; 4-Methoxy-α-(sulfanylidene)benzenacetic Acid; Acetic acid, [(4-methoxybenzoyl)thio]-; (4-Methoxy-benzoylmercapto)-acetic acid
EINECS	Contact for details

Quality Control

Our production of [(4-Methoxybenzoyl)Thio]Acetic Acid adheres to stringent quality management protocols. Every batch is analyzed using advanced chromatographic and spectroscopic techniques to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters are provided and available upon request, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.