Description

5-[3-Chloro-2-(Trimethylsiloxy)Propyl]-1,3-Dimethyl-5-(1-Methylbutyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is a specialized organosilicon-substituted barbiturate derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique molecular architecture, which combines a reactive chloropropyl group with a silyl-protected hydroxyl function, enabling precise chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients, particularly those requiring selective functionalization and controlled release properties.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel barbiturate analogs and other central nervous system (CNS) active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, where its functional groups allow for the creation of compounds with specific biological activity.
• Chemical Research & Development: Serves as a versatile precursor in academic and industrial R&D for exploring new organosilicon chemistry and heterocyclic compound libraries.
• Material Science: Potential intermediate in the synthesis of specialty polymers or coatings where silicon incorporation can modify material properties.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex molecules in fine chemical manufacturing.

Basic Information

Item	Details
Product Name	5-[3-Chloro-2-(Trimethylsiloxy)Propyl]-1,3-Dimethyl-5-(1-Methylbutyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione
CAS No.	57397-44-1
Molecular Formula	C17H31ClN2O4Si
Molecular Weight	390.98 g/mol
Synonyms	1,3-Dimethyl-5-(1-methylbutyl)-5-[3-chloro-2-(trimethylsiloxy)propyl]barbituric acid; 5-[3-Chloro-2-(trimethylsilyloxy)propyl]-1,3-dimethyl-5-(1-methylbutyl)barbituric acid; 5-(3-Chloro-2-trimethylsilanyloxy-propyl)-1,3-dimethyl-5-(1-methyl-butyl)-1,3,5-triazine-2,4,6-trione; Barbituric acid derivative, CAS 57397-44-1; TMS-protected chloropropyl barbiturate
EINECS	Contact for details

Quality Control

Our 5-[3-Chloro-2-(Trimethylsiloxy)Propyl]-1,3-Dimethyl-5-(1-Methylbutyl)-2,4,6(1H,3H,5H)-Pyrimidinetrione is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets exacting research and process chemistry standards. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.