Description

2H-Pyran-4-Ol, 4-Ethynyltetrahydro- (9Ci) is a specialized organic compound featuring a tetrahydro-2H-pyran core substituted with an ethynyl group at the 4-position. This unique structure, combining an alkyne functionality with a heterocyclic alcohol, makes it a valuable and versatile building block for advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures, particularly in medicinal chemistry and material science applications.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in programs targeting central nervous system (CNS) disorders or anti-infective agents.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides, where its heterocyclic structure is integral to biological activity.
• Material Science Research: Serves as a precursor for novel polymers, ligands, or metal-organic frameworks (MOFs) due to its reactive ethynyl group, which can undergo click chemistry reactions.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex natural product analogs and other fine chemicals through reactions like Sonogashira coupling or nucleophilic addition.
• Ligand and Catalyst Development: The oxygen and potential coordination sites make it useful for designing new ligands for asymmetric catalysis or metal complexation.

Basic Information

Item	Details
Product Name	2H-Pyran-4-Ol, 4-Ethynyltetrahydro- (9Ci)
CAS No.	57385-16-7
Molecular Formula	C7H10O2
Molecular Weight	126.15 g/mol
Synonyms	4-Ethynyltetrahydro-2H-pyran-4-ol; 4-Ethynyloxan-4-ol; Tetrahydro-4-ethynyl-2H-pyran-4-ol; 4-Ethynyltetrahydropyran-4-ol; 4-Hydroxy-4-ethynyltetrahydropyran; 4-Ethynyl-4-hydroxytetrahydropyran; 4-(Hydroxymethyl)tetrahydro-2H-pyran-4-carbonitrile (related structure); Oxan-4-ol, 4-ethynyl-
EINECS	Contact for details

Quality Control

Our production of 2H-Pyran-4-Ol, 4-Ethynyltetrahydro- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive R&D and scale-up processes. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) documenting identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.